![]() ![]() The number of piezoelectric platforms is quite wide and many papers on the issue have been written. On the other hand, sensitivity in micrograms necessary to make measurable change in oscillations and some specific aspects like fragility should be taken into consideration. It can simply record affinity interactions without the necessity to apply any specific reagents. The piezoelectric platform appears to be ideal for the construction of biosensors. The change (decay) in frequency is proportional to mass bound the crystal as described by Sauerbreay and coworkers but change in medium viscosity can also influence the oscillations as defined by Kanazawa and coworkers. Analyte or any other mass bound on surface of crystal or more precisely on surface of electrodes located on the crystal results in change of oscillation frequency. The alternating voltage causes mechanical oscillations of crystal and frequency of oscillations is measured as the crystal is put into oscillation circuit. The biosensor or sensor is excited by alternating voltage given on the surface by two electrodes. ![]() The principle of such assay can be introduced by following a simplifying explanation. Ĭonsidering an analytical chemistry point of view, the piezoelectricity is well suitable for physical sensors and biosensors construction. Aluminum phosphate (berlinite), aluminum nitride, zinc oxide, crystalized topaz (Al 2SiO 4(F, OH) 2), barium and lead titanate, gallium orthophosphate, quartz (SiO 2), tartrate tetrahydrate (Rochelle salt), polyvinylidene fluoride, polylactic acids can be mentioned as typical piezoelectric materials. Anisotropic crystals, that is, crystals without center of symmetry, are typical materials exerting piezoelectricity. Voltage given to surface of a piezoelectric material causes mechanical stress or oscillation when the voltage is alternating. The effect works in the oppose situation as well. Piezoelectricity or piezoelectric effect is a physical phenomenon which refers to an ability of a material to produce voltage when mechanically stressed.
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